Protein Modification Reagents
Medchemexpress LLC Mal-amido-PEG2-NHS ester | 955094-26-5 | MFCD11041137 | 99.3% | 425.39 g/mol | C18H23N3O9 | 50 MG
Mal-amido-PEG2-NHS ester is a noncleavable ADC linker containing a maleimide reactive group and an N-hydroxysuccinimide (NHS) ester. The NHS ester labels primary amines (-NH2) to form stable amide bonds, while the maleimide enables thiol conjugation for bioconjugation and linker chemistry applications.
- Noncleavable ADC linker with maleimide and NHS ester.
- Reacts with primary amines to form stable amide bonds.
- Enables thiol conjugation via the maleimide functionality.
- High purity suitable for research-grade bioconjugation.
- Supplied as a solid for easy handling and storage.
eMolecules Broadpharm / DBCO-NHCO-PEG4-acid / 25mg / 353441826 / BP-23760 / / 2110448-99-0 / MFCD31380393 / 552.624 / C30H36N2O8
Broadpharm / DBCO-NHCO-PEG4-acid / 25mg / 353441826 / BP-23760 / / 2110448-99-0 / MFCD31380393 / 552.624 / C30H36N2O8
Sino Biological Assay Buffer and Co-factors: DTT Solution
0.1 M DTT solution used for preparing protein kinase assay buffer.
Medchemexpress LLC Tamra-peg4-acid | 1909223-02-4 | 95.3% | C36H43N3O10 | 25 MG
TAMRA-PEG4-acid is a dye derivative of TAMRA containing 3 PEG units. It is for research use only and not sold to patients.
- Dye derivative of TAMRA
- Contains 3 PEG units
- Used in fluorescent dye applications
- Related to labeling chemistry
- A functional group type
- Belongs to rhodamine dyes
Medchemexpress LLC DBCO-PEG4-NHS ester | 1427004-19-0 | 99.0% | C34H39N3O10 | 1 G
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This product is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with azide-containing molecules
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- For research use only
LAYSAN BIO INC Thiol-PEG-Thiol, 3400 Da, 5 g, Linear, Homobifunctional, Powder, Highly soluble in water
LAYSAN BIO INC's Thiol-PEG-Thiol (SH-PEG-SH) is a high-purity, homobifunctional polyethylene glycol derivative with thiol groups, designed for efficient conjugation of biomolecules. This product offers excellent water solubility and biocompatibility, making it suitable for various biological applications. Its thiol reactivity allows participation in diverse chemical reactions, enhancing the stability and functionality of proteins in drug delivery and diagnostic assays.
- High purity and biocompatibility
- Efficient conjugation of biomolecules
- Excellent water solubility
- Thiol groups for versatile chemical reactivity
- Enhances protein stability and half-life
- Suitable for drug delivery systems and diagnostics
- Packed in 5 g for convenience
- Store at -20°C for optimal longevity
Medchemexpress LLC 4,7,10,13-tetraoxapentadecanoic acid, 15-hydroxy-, 1,1-dimethylethyl ester | 518044-32-1 | 99.3% | 322.39 g/mol | C15H30O7 | 10 G
Hydroxy-PEG4-(CH2)2-Boc is a PEG-based linker reagent used for conjugation chemistry, including antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs). It provides a hydrophilic four-unit polyethylene glycol spacer with a terminal hydroxy group and a Boc-protected tert-butyl ester, intended for research use only.
- Provides a four-unit PEG spacer with terminal hydroxy functionality.
- Contains a Boc-protected tert-butyl ester compatible with common synthetic workflows.
- High reported purity suitable for conjugation and linker chemistry.
- Available in multiple pack sizes, including 10 G.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC Pomalidomide-PEG4-azide | 2271036-47-4 | 99.8% | C23H30N6O8 | 250 MG
Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates a Pomalidomide-based cereblon ligand and a linker used in PROTAC technology. This click chemistry reagent contains an Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. Pomalidomide-PEG4-azide is intended for research use only.
- Incorporates a Pomalidomide-based cereblon ligand
- Utilizes a linker used in PROTAC technology
- Features an Azide group for click chemistry reactions
- Enables copper-catalyzed azide-alkyne cycloaddition
- Facilitates strain-promoted alkyne-azide cycloaddition
- Intended for research use only
Medchemexpress LLC DBCO-PEG2-acid | 2304558-25-4 | ≥95.0% | C26H28N2O6 | 250 MG
DBCO-PEG2-acid is a PEG-based PROTAC linker designed for synthesizing PROTACs. It acts as a click chemistry reagent, featuring a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs typically comprise two distinct ligands connected by a linker, where one targets an E3 ubiquitin ligase and the other targets the protein of interest, enabling selective degradation through the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Click chemistry reagent
- Incorporates a DBCO group
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Used in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Suitable for laboratory chemical applications
Medchemexpress LLC Biotin-PEG4-Amide-C6-Azide | 1006592-62-6 | 99.1% | C27H49N7O7S | 25 MG
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne group molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group molecules.
- PEG-based PROTAC linker
- Click chemistry reagent with azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC Pomalidomide-PEG6-C2-COOH | 2225148-49-0 | 99.0% | C28H39N3O12 | 25 MG
Pomalidomide-PEG6-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a 6-unit PEG linker used in PROTAC technology. It has a molecular weight of 609.62 and appears as a viscous liquid, light yellow to yellow in color. This product is for research use only.
- E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Contains a 6-unit PEG linker
- Used in PROTAC technology
Medchemexpress LLC Mal-amido-PEG24-acid | 2171095-70-6 | 98.5% | C58H108N2O29 | 25 MG
Mal-amido-PEG24-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules contain two different ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.
- Peg-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Intended for research use only